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SOCS-1 Polyclonal Antibody

CAT: 1027-RA20625-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA20625-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Suppressor of cytokine signaling 1 (SOCS1) Homo sapiens This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN) -gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
Product Name Alternative
SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3
Gene ID
8651
Swiss Prot
O15524
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
IF/ICC; WB; IHC-p; ELISA
Dilution
IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
38
Storage Conditions
-20°C/1 year
Protein Weight
38

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