EIF4E Monoclonal Antibody

• Background:

  Eukaryotic translation initiation factor 4E (EIF4E) Homo sapiens The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

• Product Name Alternative:

  EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein

• Gene ID:

  1977

• Swiss Prot:

  P06730

• Cross Reactivity:

  Human

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB; IHC-p; IF/ICC; FCM; ELISA

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

• Buffer:

  Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

• Storage Conditions:

  -20°C/1 year