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Rag A/B Antibody

CAT: 1071-OM635839-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM635839-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14. 7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Belongs to the GTR/RAG GTP-binding protein family. subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14. 7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane. subunit:Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14. 7 kDa protein. tissue specificity:Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.
Immunogen
The antiserum was produced against synthesized peptide derived from human RRAGA/B. AA range:264-313
Antibody Type
Primary Antibodies
Product Name Synonym
RRAGA antibody; Ras-related GTP-binding protein A antibody; Rag A antibody; RagA antibody; Adenovirus E3 14.7 kDa-interacting protein 1 antibody; FIP-1 antibody; RRAGB antibody; Ras-related GTP-binding protein B antibody; Rag B antibody; RagB antibody

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