Products for Research Use Only

PepPool: CEFRAS Global (CD4 and CD8), human

CAT: 0930-3638-1Size: 2 VialsDry Ice: NoHazardous: No
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CAT#:0930-3638-1Size:2 Vials
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The CEFRAS (CD4 and CD8) peptide pool stimulates CD4+ and CD8+ T cells to produce e.g., IFN-γ, IL-2, IL-4, IL-5 and TNF-α. It is recommended as a positive control in ELISpot and FluoroSpot assays using human PBMC. The peptide pool can also be used in flow cytometry. The 203 peptides in the pool are MHC class I and MHC class II T-cell epitopes from twenty-two pathogens: Coxsackievirus B4, Clostridium tetani, Haemophilus influenza, Helicobacter pylori, Human adenovirus 5, Human herpesvirus 1, Human herpesvirus 2, Human herpesvirus 3, Human herpesvirus 4 (Epstein-Barr Virus, EBV), Human herpesvirus 5 (Cytomegalovirus, CMV), Human herpesvirus 6, Human papillomavirus, Influenza A, JC polyomavirus, Measles virus, Mycobacterium tuberculosis, Respiratory syncytical virus, SARS-CoV-2, Rubella virus, Toxoplasma gondii, Vaccinia virus, and Yellow fever. The peptide pool is designed for T cell stimulation, covering a broad range of HLA types from diverse ethnic backgrounds. Peptides are synthesized with capping after coupling. The median HPLC purity is 88%.
Reactivity
Human
Applications
This peptide pool is intended for use as a positive control in immunoassays such as ELISpot and FluoroSpot. It induces cytokine secretion from antigen-specific human CD4 and CD8 T cells. For research use only. Not for use in diagnostic procedures.
Shipping Conditions
Shipped at ambient temperature.
Storage Conditions
Store at -20 °C or below upon receipt.