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Phospho-GluR1 (Ser849) Polyclonal Antibody

CAT: 0498-bs-8446RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-8446RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Synonyms
GluR1 phospho Ser849; GluR1 phospho S849; p- GluR1Ser849; p- GluR1S849; GLUR 1; GLUR A; AMPA 1; AMPA selective glutamate receptor 1; GLUH 1; GLUH1; GluR K1; GluR-1; GluR-A; GluR-K1; GLUR1; GLURA ; GluRK1; Glutamate receptor 1; Glutamate receptor ionotropic AMPA 1; Gria 1; Gria1 ; Gria1; HBGR1; MGC133252.
Gene ID
2890
Modification Site
Ser849
Cellular Locus
Cytoplasm, Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-GluR1 (Ser849)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic phosphopeptide derived from human GluR1 around the phosphorylation site of Ser849 [QQ (p-S) IN]
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
2890
Predicted Cross Reactivity
Dog, Cow, Sheep, Pig, Horse, Chicken

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