FOX1 Antibody

• Background:

  FOX1, also known as ataxin-2 binding protein 1 (A2BP1), is a neuron specific RNA-binding protein that has been shown to regulate a wide range of alternative splicing events implicated in neuronal development and maturation including transcription factors and synaptic proteins (Fogel et al., 2012) . Defects in FOX1 have also been associated with autism (Martin et al., 2007), attention-deficit hyperactivity disorder (Elia et al., 2010) and schizophrenia (Xu et al., 2008) .

• Synonyms:

  2BP1 antibody, A2 BP1 antibody, A2BP 1 antibody, A2BP antibody, A2BP1 antibody, Ataxin 2 binding protein 1 antibody, Ataxin-2-binding protein 1 antibody, Ataxin2 binding protein 1 antibody, FOX1 antibody, Fox-1 homolog A antibody, fox-1-like RNA-binding protein 1 antibody, Hexaribonucleotide binding protein 1 antibody, Hexaribonucleotide-binding protein 1 antibody, HRNBP 1 antibody, HRNBP1 antibody, RBFOX1 antibody, RFOX1_HUMAN antibody, RNA binding protein fox-1 homolog 1 antibody, RNA binding protein fox-1 homolog 1 C. elegans, homolog of 1 antibody, RNA binding protein fox-1 homolog (C. elegans) 1 antibody

• Gene ID:

  54715

• Swiss Prot:

  Q9NWB1

• Host:

  Mouse

• Cross Reactivity:

  Human, Mouse, Rat, Bovine

• Target:

  FOX1

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  1G10

• Conjugation:

  Unconjugated

• Source:

  Recombinant protein taken from the N-terminus of human FOX1 expressed in and purified from E. Coli.

• Applications:

  WB, IHC

• Purification:

  Purified by Protein G.

• Concentration:

  Lot Dependent

• Dilution:

  WB (1:300-5000), IHC ()

• Buffer:

  PBS + 10 mM NaN3.

• Modification:

  Unmodified

• Storage Conditions:

  Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

• Specificity:

  Specific for endogenous levels of the ~46/48 kD FOX1 protein doublet.

• Gene ID URL:

  54715