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4-Thiouracil

CAT: 0804-HY-W010417-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W010417-01Size:100 mg
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Description
4-Thiouracil is a thionucleobase with cytostatic properties. 4-Thiouracil can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts. 4-Thiouracil can also act as a strong ultraviolet A (UVA) photosensitizer, providing a source of the reactive oxygen species of O2. 4-Thiouracil is promising for research of photocross linking, photodamage, as well as photodynamic therapy[1].
CAS Number
[591-28-6]
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/4-thiouracil.html
Purity
99.98
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1)NC=CC1=S
Molecular Formula
C4H4N2OS
Molecular Weight
128.15
Precautions
H302+H312+H332
References & Citations
[1]Zou X, et al. Photophysical and photochemical properties of 4-thiouracil: time-resolved IR spectroscopy and DFT studies. J Phys Chem B. 2014 Jun 5;118 (22) :5864-72.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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