Cripto Recombinant Antibody

• Background:

  GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

• Synonyms:

  CRGF; Cripto 1; cripto; Cripto1 growth factor; TDGF1.

• Gene ID:

  6997

• Swiss Prot:

  P13385

• Host:

  Rabbit

• Cross Reactivity:

  Human

• Target:

  Cripto

• Clonality:

  Recombinant

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human Cripto

• Applications:

  WB, IP, Flow-Cyt, ICC/IF

• Purification:

  Purified by Protein A.

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IP (1-2ug), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

• Buffer:

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  6997