Recombinant CRIPTO Antibody

• Description:

  GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. [UniProt]

• Specifications:

  Western blot: 1:500-1:2000

• UniProt:

  Q9UKX7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide specific to human Protein Cripto was used as the immunogen for the recombinant CRIPTO antibody.

• Clonality:

  Recombinant Monoclonal

• Isotype:

  IgG

• Clone:

  21T86

• Applications:

  WB

• Purity:

  Affinity chromatography

• Format:

  Purified

• Limitations:

  This recombinant CRIPTO antibody is available for research use only.

• Storage Conditions:

  Store the recombinant CRIPTO antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the recombinant CRIPTO antibody should be determined by the researcher.

• Image Legend:

  Western blot testing of human NCCIT cell lysate with recombinant CRIPTO antibody. Predicted molecular weight ~21 kDa.