Recombinant CRIPTO Antibody

• Description :

  GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. [UniProt]

• Specifications :

  Western blot: 1:500-1:2000

• UniProt :

  Q9UKX7

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A synthetic peptide specific to human Protein Cripto was used as the immunogen for the recombinant CRIPTO antibody.

• Clonality :

  Recombinant Monoclonal

• Isotype :

  IgG

• Clone :

  21T86

• Applications :

  WB

• Purity :

  Affinity chromatography

• Format :

  Purified

• Limitations :

  This recombinant CRIPTO antibody is available for research use only.

• Storage Conditions :

  Store the recombinant CRIPTO antibody at -20°C.

• Formulation :

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes :

  Optimal dilution of the recombinant CRIPTO antibody should be determined by the researcher.

• Image Legend :

  Western blot testing of human NCCIT cell lysate with recombinant CRIPTO antibody. Predicted molecular weight ~21 kDa.