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Uric acid-15N2

CAT: 0804-HY-B2130S1-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2130S1-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Uric acid-15N2 is the 15N labeled Uric acid[1]. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[2][3].
CAS Number
62948-75-8
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/uric-acid-15n2.html
Purity
99.60
Solubility
H2O : 5.88 mg/mL (ultrasonic; adjust pH to 10 with 1M NaOH)
Smiles
O=C1C2=C([15NH]C([15NH]1)=O)NC(N2)=O
Molecular Formula
C5H4N2 15N2O3
Molecular Weight
170.10
Precautions
H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32 (11) :1839-1845.|[3]Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 202050 (4) :359-375.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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