Uric acid

• Description :

  Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Endogenous Metabolite; Reactive Oxygen Species (ROS)

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/Uric_acid.html

• Purity :

  99.96

• Solubility :

  1M NaOH : 8.33 mg/mL (ultrasonic; warming; adjust pH to 12 with 1M NaOH; heat to 60°C) |H2O : 6.25 mg/mL (ultrasonic; adjust pH to 11 with 1 M NaOH)

• Smiles :

  O=C(N1)NC2=C(NC(N2)=O)C1=O

• Molecular Formula :

  C5H4N4O3

• Molecular Weight :

  168.11

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32 (11) :1839-1845.|[2]Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 2020;50 (4) :359-375.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite

• Citation 01 :

  Adv Sci (Weinh) . 2025 Apr;12 (16) :e2415041.|Biomed Pharmacother. 2025 Nov 12:193:118745.|BMC Neurol. 2023 Dec 16;23 (1) :444.|Cell Mol Biol Lett. 2025 Oct 2;30 (1) :109.|Cell Rep Med. 2024 Aug 20;5 (8) :101690.|Drug Des Devel Ther. 2025 Jul 30:19:6573-6585.|Drug Dev Res. 2020 Nov;81 (7) :859-866.|Exp Biol Med. 2022 Jan;247 (2) :174-183.|Int J Mol Sci. 2022 Jun 20;23 (12) :6860.|J Agric Food Chem. 2025 Aug 27.|J Hazard Mater. 2024 Sep 23:480:135938.|Nature. 2025 Jul;643 (8070) :192-200.|Research Square Preprint. 2022 Feb.|Research Square Preprint. 2023 Jul 28.|Respir Res. 2025 May 24;26 (1) :196.|Arab J Chem. 2024 Jul 20.|Genes Immun. 2025 Aug;26 (4) :365-375.|J Adv Res. 2025 Jul 14:S2090-1232 (25) 00544-2.|J Adv Res. 2025 Nov 7:S2090-1232 (25) 00877-X.|J Ginseng Res. 2025 Jul;49 (4) :426-437.

• CAS Number :

  [69-93-2]