SAMHD1/MOP5 Recombinant Antibody, APC Conjugated

• Background:

  Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks.Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses, such as HIV-1: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells .

• Synonyms:

  SAMHD1; AGS5; CHBL2; DCIP; HDDC1; MOP-5; MOP5; SBBI88; Mg11.

• Gene ID:

  25939

• Swiss Prot:

  Q9Y3Z3

• Cellular Locus:

  Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Human

• Target:

  SAMHD1/MOP5

• Clonality:

  Recombinant

• Isotype:

  IgG

• Conjugation:

  APC

• Source:

  KLH conjugated synthetic peptide derived from human SAMHD1

• Applications:

  WB, IF, Flow-Cyt

• Purification:

  Purified by Protein A.

• Excitation Emission:

  650nm/660nm

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  25939