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SYNC Polyclonal Antibody

CAT: 0498-bs-9463RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-9463RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Syncoilin (SYNC) is a 483 amino acid member of the intermediate filament family. Localized to the perinuclear region of cytoplasm, Syncoilin interacts with Alpha-Dystrobrevin and Desmin. Syncoilin links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle, and is therefore found at high levels in cardiac and skeletal muscle. Syncoilin is upregulated at the sarcolemma in individuals with various forms of neuromuscular disease. The gene that encodes Syncoilin maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
Synonyms
Intermediate filament protein syncoilin; SYNC; SYNC1; SYNCI_HUMAN; Syncoilin; Syncoilin intermediate filament 1; Syncoilin-1.
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
211-310/482
Target
SYNC
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human SYNC/Syncoilin
Applications
WB, ELISA, IHC-P, IHC-F, IF, ICC/IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:50-200), ICC/IF (ICC/IF=1:100-500)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

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