Products for Research Use Only
RegisterLogin

SPO11 Polyclonal Antibody

CAT: 0498-bs-9302RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-9302RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.
Synonyms
Meiotic recombination protein SPO 11; Meiotic recombination protein SPO11; MGC39953; SPO 11; SPO11 meiotic protein covalently bound to DSB homolog; SPO11 meiotic protein covalently bound to DSB like; SPO11_HUMAN.
Gene ID
23626
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
151-330/396
Target
SPO11
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human SPO11
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
23626
Predicted Cross Reactivity
Dog, Pig, Horse

Related Products

CatalogName
bs-7520RSPON1 Polyclonal Antibody
bs-7520R-Cy5SPON1 Polyclonal Antibody, Cy5 Conjugated
bs-7520R-BiotinSPON1 Polyclonal Antibody, Biotin Conjugated
bs-7520R-PESPON1 Polyclonal Antibody, PE Conjugated
bs-7520R-Cy7SPON1 Polyclonal Antibody, Cy7 Conjugated
bs-7520R-APCSPON1 Polyclonal Antibody, APC Conjugated
bs-7520R-RBITCSPON1 Polyclonal Antibody, RBITC Conjugated
bs-7520R-HRPSPON1 Polyclonal Antibody, HRP Conjugated
bs-7520R-FITCSPON1 Polyclonal Antibody, FITC Conjugated
bs-7520R-PerCPSPON1 Polyclonal Antibody, PerCP Conjugated

Alternative Products

CatalogName
MBS8574159-01SPO11 Polyclonal Antibody
TMAB-13128-01Anti-SPO11 Polyclonal Antibody
H00023626-D01PRabbit Polyclonal SPO11 Antibody
TA362968Spo11 Rabbit Polyclonal Antibody
GTR18284511SPO11 Polyclonal Conjugated Antibody
H00023626-B01PMouse Polyclonal SPO11 Antibody
TA321020SPO11 Goat Polyclonal Antibody
GTR18610003SPO11 Rabbit Polyclonal Antibody (PE)
GTR18753507SPO11 Rabbit Polyclonal Antibody (Fluoro594)
70R-5594SPO11 antibody

Popular Products