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GRAMD2 Polyclonal Antibody, Biotin Conjugated

CAT: 0498-bs-8578R-BiotinSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-8578R-BiotinSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GRAMD2 is a 354 amino acid single-pass membrane protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 15q23. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
Synonyms
GRAM domain containing 2; GRAM domain containing protein 2; GRAMD 2; GRAM2_HUMAN.
Gene ID
196996
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Immunogen
151-250/354
Target
GRAMD2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human GRAMD2
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
196996
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Sheep, Horse, Chicken

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