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RBM38 Polyclonal Antibody

CAT: 0498-bs-7682RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-7682RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
Synonyms
SEB4D; CLL associated antigen KW 5; CLL-associated antigen KW-5; HSRNASEB; RBM38; RBM38_HUMAN; RNA binding mot protein 38; RNA binding protein 38; RNA binding region RNP1, RRM containing 1; RNA binding region containing protein 1; RNA-binding mot protein 38; RNA-binding protein 38; RNA-binding region-containing protein 1; RNPC1; SEB4; SEB4B; ssDNA binding protein SEB4; ssDNA-binding protein SEB4.
Gene ID
55544
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Immunogen
51-150/239
Target
RBM38
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human RBM38
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
55544
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Chicken, Rabbit

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