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UZH1a

CAT: 0804-HY-134673A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-134673A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1a can be used for epitranscriptomic modulation of cellular processes. UZH1a has antitumor activity. UZH1a also can be used as a chemical probe for studying METTL3[1].
CAS Number
2813577-78-3
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/uzh1a.html
Purity
99.90
Solubility
DMSO : 80 mg/mL (ultrasonic)
Smiles
O=C(NC[C@@]1(O)CN(C2=NC=NC(NCC3=CC=CC=C3)=C2)CCC1)C4=CC=C(CN5CCC(C)(C)CC5)C=C4O
Molecular Formula
C32H42N6O3
Molecular Weight
558.71
References & Citations
[1]Moroz-Omori EV, et, al. METTL3 inhibitors for epitranscriptomic modulation of cellular processes. bioRxiv. 2020 Oct 13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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