CDCA7L Polyclonal Antibody, Biotin Conjugated

• Background:

  CDCA7L is a member of the CDCA (cell division cycle associated) protein family. Members of this family have expression patterns associated with other known cell cycle genes such as cyclins and CDC genes. CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It is involved in apoptotic signaling pathways and may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

• Synonyms:

  C Myc Interacting protein JPO2; DKFZp762L0311; RAM2; HR1; JPO2; Protein JPO2; R1 antibody Transcription Factor RAM2.CDA7L_HUMAN

• Gene ID:

  55536

• Cellular Locus:

  Cytoplasm, Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Immunogen:

  381-454/454

• Target:

  CDCA7L

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Biotin

• Source:

  KLH conjugated synthetic peptide derived from human CDCA7L

• Applications:

  ELISA, IHC-P, IHC-F

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C for 12 months.

• Gene ID URL:

  55536

• Predicted Cross Reactivity:

  Dog, Cow, Pig, Horse, Chicken, Rabbit