CKAP5 Polyclonal Antibody

• Background:

  CKAP5 is a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

• Synonyms:

  Ch TOG protein; chTOG; CHTOG protein; CKAP5_HUMAN; CKAP 5; CKAP5; CKAP5 protein; Colonic and hepatic tumor over expressed; Colonic and hepatic tumor over expressed protein; Colonic and hepatic tumor overexpressed protein; Cytoskeleton associated protein 5; FLJ35359; KIAA0097; TOG; TOGp.

• Gene ID:

  9793

• Cellular Locus:

  Cytoplasm

• Host:

  Rabbit

• Immunogen:

  81-180/2032

• Target:

  CKAP5

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human CKAP5/ch TOG

• Applications:

  WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  9793

• Predicted Cross Reactivity:

  Human, Mouse, Rat, Dog, Horse, Rabbit