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APEX1 Polyclonal Antibody

CAT: 0498-bs-55012RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-55012RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Synonyms
APEX1; APE; APE1; APEN; APEX; APX; HAP1; REF1
Gene ID
328
Swiss Prot
P27695
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
APEX1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1 (NP_542380.1) .
Applications
WB, IF (ICC), IP, IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (ICC) (1:50-200), IP (1-2ug), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
328

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