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Jarid1b Polyclonal Antibody

CAT: 0498-bs-51067RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-51067RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity) .
Synonyms
CT31, PLU1, PUT1, RBBP2H1, RBP2-like
Gene ID
10765
Swiss Prot
Q9UGL1
Host
Rabbit
Cross Reactivity
Mouse
Target
Jarid1b
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against mouse Jarid1b, using a KLH-conjugated synthetic peptides containing an amino acid sequence from the central part of the protein
Applications
WB, ELISA
Purification
Whole antiserum from rabbit containing 0.05% azide
Concentration
Not Determined
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
10765