APH1A Polyclonal Antibody

CAT: 0498-bs-4259RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-4259RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein) . It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Synonyms
APH-1; APH-1A; CGI-78; 6530402N02Rik; Gamma-secretase subunit APH-1A; Aph-1alpha; Presenilin-stabilization factor; APH1A; PSF; UNQ579/PRO1141
Gene ID
51107
Swiss Prot
Q96BI3
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
71-170/265
Target
APH1a
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human APH1a
Applications
WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51107
Predicted Cross Reactivity
Mouse, Dog, Cow, Pig, Horse, Rabbit

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