ACE2 Polyclonal Antibody

• Background:

  The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008].

• Synonyms:

  ACE-2; ACE 2; Angiotensin converting enzyme 2; ACE related carboxypeptidase; ACEH; Angiotensin converting enzyme homolog; Angiotensin converting enzyme like protein; Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2; Angiotensin I converting enzyme 2; DKFZP434A014; EC 3.4.17; OTTHUMP00000022963; angiotensin-converting enzyme 2 precursor; ACE2_HUMAN; Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; Metalloprotease MPROT15; Processed angiotensin-converting enzyme 2.

• Gene ID:

  59272

• Swiss Prot:

  Q9BYF1

• Cellular Locus:

  Secreted, Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Target:

  ACE2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  Recombinant human ACE2

• Applications:

  WB, IHC-P, IHC-F, IF

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (WB=1:500-2000), IHC-P (IHC-P=1:400-800), IHC-F (IHC-F=1:400-800), IF (IF=1:100-500)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C for 12 months.

• Gene ID URL:

  59272