TAB1 Polyclonal Antibody

CAT: 0498-bs-4135RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-4135RSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.
Synonyms
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1; TAB1; MAP3K7IP1
Gene ID
10454
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
351-450/504
Target
TAB1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human MAP3K7IP1/TAB1
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
10454
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit

Related Products

CatalogName
bsm-60541MTAB1 Monoclonal Antibody
bs-102059P-01Recombinant Human TAB1 Protein, N-His
bs-6734RSERBP1 Polyclonal Antibody
bs-6739RTIMM17A Polyclonal Antibody
bs-7734RCAPD3 Polyclonal Antibody
bs-7738R-01Anillin Polyclonal Antibody
bs-7750RKIF20A Polyclonal Antibody
bs-1868RPDCD1LG2 Polyclonal Antibody
bs-18719RMCCC2 Polyclonal Antibody
bs-18736RMCT5 Polyclonal Antibody

Alternative Products

CatalogName
MBS2542933-01TAB1 Polyclonal Antibody
APR06357GPolyclonal TAB1 Antibody
TA306187TAB1 Rabbit Polyclonal Antibody
NBP1-76595Rabbit Polyclonal TAB1 Antibody

Popular Products