Products for Research Use Only
RegisterLogin

LRP5 Polyclonal Antibody

CAT: 0498-bs-4117RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-4117RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.
Synonyms
HBM; LR3; OPS; EVR1; EVR4; LRP7; OPPG; BMND1; LRP-5; OPTA1; VBCH2; Low-density lipoprotein receptor-related protein 5; LRP5
Gene ID
4041
Swiss Prot
O75197
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
501-600/1615
Target
LRP5
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LRP5
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Specificity
This antibody will recognize LRP6 due to high sequence similarity.
Gene ID URL
4041
Predicted Cross Reactivity
Rat, Dog, Cow, Horse, Chicken, Rabbit

Related Products

CatalogName
bs-25114RPhospho-LRP5 (Thr1492) Polyclonal Antibody
bs-25114R-BiotinPhospho-LRP5 (Thr1492) Polyclonal Antibody, Biotin Conjugated
bs-25114R-RBITCPhospho-LRP5 (Thr1492) Polyclonal Antibody, RBITC Conjugated
bs-25114R-PEPhospho-LRP5 (Thr1492) Polyclonal Antibody, PE Conjugated
bs-25114R-Cy3Phospho-LRP5 (Thr1492) Polyclonal Antibody, Cy3 Conjugated
bs-25114R-APCPhospho-LRP5 (Thr1492) Polyclonal Antibody, APC Conjugated
bs-25114R-PerCPPhospho-LRP5 (Thr1492) Polyclonal Antibody, PerCP Conjugated
bs-25114R-FITCPhospho-LRP5 (Thr1492) Polyclonal Antibody, FITC Conjugated
bs-25114R-Cy5Phospho-LRP5 (Thr1492) Polyclonal Antibody, Cy5 Conjugated
bs-25114R-HRPPhospho-LRP5 (Thr1492) Polyclonal Antibody, HRP Conjugated

Alternative Products

CatalogName
MBS2526904-01LRP5 Polyclonal Antibody
JOT-AP11137-01LRP5 Rabbit Polyclonal Antibody
TA305828LRP5 Goat Polyclonal Antibody
HF797014-01Anti-LRP5 Polyclonal Antibody
MBS9236635-01LRP5 + LRP6 Polyclonal Antibody

Popular Products