(S,R,S)-AHPC-Me-C7 ester

(S,R,S)-AHPC-Me-C7 ester

• CAS Number: 2639528-48-4
• UNSPSC Description: (S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-me-c7-ester.html
• Purity: 95.49
• Solubility: DMSO : 6.67 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C([C@@H](NC(CCCCCC(OCC)=O)=O)C(C)(C)C)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](C1)O
• Molecular Weight: 614.80
• References & Citations: [1]Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported