DIO2 Polyclonal Antibody, HRP Conjugated

• Background:

  DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) . It is essential for providing the brain with appropriate levels of T3 during the critical period of development. DIO2 is expressed in heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. There are two named isoforms.

• Synonyms:

  5DII; D2; Deiodinase, iodothyronine, type II; DIOII; ITDI2; SelY; Thyroxine deiodinase, type II; TXDI2; Type 2 DI; Type II 5' deiodinase; Type II iodothyronine deiodinase.

• Gene ID:

  1734

• Cellular Locus:

  Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Immunogen:

  101-200/273

• Target:

  DIO2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  HRP

• Source:

  KLH conjugated synthetic peptide derived from human DIO2

• Applications:

  WB, ELISA, IHC-P, IHC-F

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  1734

• Predicted Cross Reactivity:

  Dog, Cow, Sheep, Pig, Horse, Rabbit