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GMB-475

CAT: 0957-S8888-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8888-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1 protein and recruit the E3 ligase Von Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.
CAS Number
2490599-18-1
Target
Bcr-Abl
Activity
Protein Tyrosine Kinase
Molecular Formula
C43H46F3N7O7S
Storage Conditions
3 years -20°C powder