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Suzetrigine phenol

CAT: 0804-HY-160903-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160903-01Size:1 mg
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Description
Suzetrigine phenol is the phenolate form of the sodium channel modulator Suzetrigine. Suzetrigine (VX-548) is an orally active and highly selective inhibitor of NaV1.8[1][2].
CAS Number
2649467-91-2
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/suzetrigine-phenol.html
Purity
99.39
Solubility
DMSO : 87.5 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(C(N)=O)=NC=C1)[C@H]2[C@H](C3=C(O)C(F)=C(F)C=C3)[C@H](C)[C@](C)(C(F)(F)F)O2
Molecular Formula
C20H18F5N3O4
Molecular Weight
459.37
References & Citations
[1]Scarnati MS, et al. Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: Current status and outlook. Alcohol. 2019 Feb;74:83-93.|[2]Preparation of substituted tetrahydrofuran amides as modulators of sodium channels. World Intellectual Property Organization, WO2021113627 A1 2021-06-10.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported