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Pemetrexed

CAT: 0957-S5971-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-S5971-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pemetrexed (LY231514) is a novel antifolate and antimetabolite for thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT) with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.
CAS Number
137281-23-3
Synonyms
LY231514
Target
Thymidylate Synthase
Activity
Apoptosis
Molecular Formula
C20H21N5O6
Storage Conditions
3 years -20°C powder

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