Products for Research Use Only
RegisterLogin

Importin 8 Polyclonal Antibody

CAT: 0498-bs-20110RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-20110RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19.
Synonyms
FLJ26580; Imp 8; Imp8; Importin-8; Importin8; IPO 8; IPO8; IPO8_HUMAN; Ran binding protein 8; RAN BP8; Ran-binding protein 8; RANBP 8; RANBP8.
Gene ID
10526
Swiss Prot
O15397
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
1-100/1037
Target
Importin 8
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Importin 8
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
10526
Predicted Cross Reactivity
Human, Mouse, Cow, Sheep, Pig

Related Products

CatalogName
bsm-62622R-TRImportin 9 Recombinant Antibody
bsm-62622R-01Importin 9 Recombinant Antibody
bsm-62622R-Cy5Importin 9 Recombinant Antibody, Cy5 Conjugated
bsm-62622R-HRPImportin 9 Recombinant Antibody, HRP Conjugated
bsm-62622R-RBITCImportin 9 Recombinant Antibody, RBITC Conjugated
bsm-62622R-PEImportin 9 Recombinant Antibody, PE Conjugated
bsm-62622R-Cy7Importin 9 Recombinant Antibody, Cy7 Conjugated
bsm-62622R-APCImportin 9 Recombinant Antibody, APC Conjugated
bsm-62622R-BiotinImportin 9 Recombinant Antibody, Biotin Conjugated
bsm-62622R-FITCImportin 9 Recombinant Antibody, FITC Conjugated

Alternative Products

CatalogName
MBS9237336-01Importin 8 Polyclonal Antibody
MBS668074-01Importin-8 Polyclonal Antibody
MBS668062-01Importin-9 Polyclonal Antibody
MBS668140-01Importin 7 Polyclonal Antibody
11-8012-100Polyclonal Antibody to Importin-9
11-8011-25Polyclonal Antibody to Importin-8
11-8080-25Polyclonal Antibody to Importin 7
TMAB-07695-01Anti-Importin 8 Polyclonal Antibody
MBS2028193-01Polyclonal Antibody to Importin 8 (IPO8)
NBP3-17196-25ulRabbit Polyclonal Importin 11 Antibody

Popular Products