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LPHN1 Polyclonal Antibody

CAT: 0498-bs-18348RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-18348RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR) . Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
Synonyms
Calcium independent alpha latrotoxin receptor 1; Calcium-independent alpha-latrotoxin receptor 1; CIRL-1; CIRL1; CL1; CLIBA; G protein-coupled receptor for alpha-Latrotoxin; KIAA0821; Latrophilin 1; Latrophilin-1; Latrophilin1; LEC2; Lectomedin 2; Lectomedin-2; LPHN 1; LPHN1; LPHN1_HUMAN.
Gene ID
22859
Swiss Prot
O94910
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Immunogen
201-300/1474
Target
LPHN1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LPHN1
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
22859
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Pig, Horse, Rabbit