Products for Research Use Only
RegisterLogin

HUS1 Polyclonal Antibody

CAT: 0498-bs-18107RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-18107RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
Synonyms
Checkpoint protein HUS1; hHUS1; HUS1 (S. pombe) checkpoint homolog; Hus1; HUS1 checkpoint homolog (S. pombe) ; HUS1 Checkpoint Protein; HUS1 protein; HUS1+ - like protein; HUS1_HUMAN; Hydroxyurea-sensitive 1, S. pombe, homolog of.
Gene ID
3364
Swiss Prot
O60921
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
51-150/280
Target
HUS1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human HUS1
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3364
Predicted Cross Reactivity
Human, Mouse, Cow, Pig, Horse

Related Products

CatalogName
bs-103729P-01Recombinant Human HUS1 Protein, N-His
bs-8563R-01KIAA1522 Polyclonal Antibody
bs-8560RELL3 Polyclonal Antibody
bs-8557RDSPP Polyclonal Antibody
bs-8545RTRAF4 Polyclonal Antibody
bs-8539R-01Luciferase Polyclonal Antibody
bs-8537RTYMS Polyclonal Antibody
bs-8518R-01SPP24 Polyclonal Antibody
bs-8514R-01FCER1A Polyclonal Antibody
bs-8500RRFTN2 Polyclonal Antibody

Alternative Products

CatalogName
MBS2562631-01HUS1 Polyclonal Antibody

Popular Products