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Cholesteryl hemisuccinate

CAT: 0957-E6461-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0957-E6461-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cholesteryl hemisuccinate is a cholesterol derivative and a potent inhibior of DNA polymerase and DNA topoisomerase with an IC50 of 2.9 μM, 6.3 μM, 25 μM for Rat DNA polymerase β, Human DNA polymerase λ and Human DNA topoisomerase I respectively. It exhibits anticancer effect due to its ability to inhibit DNA replication, repair and cell division and can be used in cancer cell growth research.
CAS Number
1510-21-0
Target
Topoisomerase
Activity
DNA Damage/DNA Repair
Molecular Formula
C31H50O4