Products for Research Use Only

LL-K12-18

CAT: 0957-E5876-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E5876-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LL-K12-18 is a potent dual-site molecular glue that enhances CDK12-DDB1 complex formation, promoting cyclin K degradation with an EC50 of 0.37 nM. It also demonstrates strong inhibition of gene transcription and anti-proliferative effects in tumor cells, exhibiting significant potential in cancer research.
Target
CDK
Activity
Cell Cycle