CHERP Polyclonal Antibody

• Background :

  The regulation of the intracellular concentration of calcium is important for proper maintenance of voltage-gated ion channels which control muscle and nerve function. Calcium homeostasis is regulated by a variety of proteins. CHERP (calcium homeostasis endoplasmic reticulum protein), also known as SRA1, DAN16 or SCAF6, is a 916 amino acid protein that localizes to the cytoplasm and the endoplasmic reticulum (ER) . Expressed in pancreas, brain, lung, placenta, liver, kidney, heart and skeletal muscle, CHERP is involved in maintaining calcium homeostasis and plays a role in cell growth and proliferation. CHERP contains one G-patch domain, one RPR domain and one SURP motif and is expressed as two isoforms due to alternative splicing events.

• Synonyms :

  Calcium homeostasis endoplasmic reticulum protein; DAN16; DAN26; ERPROT 213 21; ERPROT21321; Protein with polyglutamine repeat; SCAF6; SR related CTD associated factor 6; SRA1.

• Gene ID :

  10523

• Swiss Prot :

  Q8IWX8

• Host :

  Rabbit

• Cross Reactivity :

  Human, Mouse, Rat

• Target :

  CHERP

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human CHERP

• Applications :

  WB, IHC-P, IHC-F, IF

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (WB=1:500-2000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:100-500)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Store at -20°C for 12 months.

• Gene ID URL :

  10523