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Bazedoxifene

CAT: 0957-E6030Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E6030Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bazedoxifene (TSE-424) is a selective estrogen receptor modulator that binds to and activates ERα and ERβ with IC50 values of 26 nM and 99 nM, respectively. It also inhibits IL-6/GP130 interactions, suppresses STAT3 signaling, induces apoptosis, and reduces tumor growth, viability, and colony formation in cancer models, while being studied for effects on bone density, uterine health, and CNS vasomotor responses.
CAS Number
198481-32-2
Synonyms
TSE-424
Target
Estrogen/progestogen Receptor
Activity
Endocrinology & Hormones
Molecular Formula
C30H34N2O3