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Tolinapant (ASTX660)

CAT: 0957-S8681-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-S8681-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tolinapant (ASTX660) is a potent, non-peptidomimetic antagonist of cIAP1/2 and XIAP that inhibits the interactions between a SMAC-derived peptide and the BIR3 domains of XIAP (BIR3-XIAP) and cIAP1 (BIR3-cIAP1) with IC50 values less than 40 and 12 nmol/L, respectively.
CAS Number
1799328-86-1
Target
IAP
Activity
Apoptosis
Molecular Formula
C30H42FN5O3
Storage Conditions
3 years -20°C powder

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