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MAML3 Polyclonal Antibody

CAT: 0498-bs-12398RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-12398RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The three MAML genes are widely expressed in adult tissues but exhibit distinct expression patterns in mouse early spinal cord development. All MAML proteins localize to nuclear bodies, share a conserved basic domain in their N termini that binds to the ankyrin repeat domain of Notch, and contain a transcriptional activation domain in their C termini. MAML3 acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1.
Synonyms
AV234550; BC049812; CAGH3; ERDA3; GDN; KIAA1816; MAM 2; MAM2; mastermind like 3 Drosophila; MGC59565; mKIAA1816; TNRC3; MAML3_HUMAN.
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
931-1030/1134
Target
MAML3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human MAML3
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Predicted Cross Reactivity
Mouse, Rat, Cow, Sheep, Pig, Horse

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