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IPMK Polyclonal Antibody

CAT: 0498-bs-12385RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-12385RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inositol polyphosphate multikinase (IPMK) belongs to the inositol phosphokinase (IPK) family and is characterized as having a broad substrate specificity. However, IPMK displays a preference for inositol-1,4,5-trisphosphate (Ins (1,4,5) P3) and inositol 1,3,4,6-tetrakisphosphate (Ins (1,3,4,6) P4) . IPMK is ubiquitously expressed with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon. IPMK is localized to the nucleus, where it may play a role in the regulation of calcium release from intracellular stores and has been implicated as a drug target for cancer therapies. The gene encoding IPMK maps to human chromosome 10, which contains over 800 genes. Notably, disorders linked to genes on chromosome 10 include Cowden syndrome, Cockayne syndrome and Tetrahydrobiopterin deficiency.
Synonyms
6-tetrakisphosphate 5-kinase; Inositol 1; Inositol 1,3,4,6 tetrakisphosphate 5 kinase; Inositol polyphosphate multikinase; Ipmk; IPMK_HUMAN
Gene ID
253430
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
101-200/416
Target
IPMK
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human IPMK
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
253430
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Horse, Rabbit

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