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Pumilio 2 Polyclonal Antibody

CAT: 0498-bs-12246RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-12246RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Pumilio 2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding mRNA targets. It supports proliferation and self-renewal of stem cells by regulating the translation of key transcripts. The Pumilio gene encodes proteins that are required for development of germ stem cells in one or both sexes. The Pumilio protein interacts with the human Nanos1 protein and this interaction may play a conserved role in germ cell development. Pumilio 2 is highly expressed in testis and ovary and at lower levels in brain, heart, kidney, liver, muscle, placenta, intestine and stomach. It is also expressed in stem cells, germ cells and in most fetal tissues.
Synonyms
FLJ36528; KIAA0235; MGC138251; MGC138253; PUM 2; Pum2; PUM2; PUMH2; Pumilio Drosphila homolog 2; Pumilio homolog 2 Drosophila; Pumilio homolog 2; Pumilio2; PUM2_HUMAN.
Gene ID
23369
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
901-1066/1066
Target
Pumilio 2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Pumilio 2
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
23369
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

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