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DC260126

CAT: 0957-S0742Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S0742Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DC260126, a small organic antagonist for GPR40 (FFAR1), dose-dependently inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50=6.28, 5.96, 7.07, 4.58 μM, respectively), reduces GTP-loading and ERK1/2 phosphorylation stimulated by linoleic acid in GPR40-CHO cells, suppresses palmitic acid potentiated glucose-stimulated insulin secretion, and negatively regulates GPR40 mRNA expression induced by oleic acid in Min6 cells.
CAS Number
346692-04-4
Target
GPR
Activity
GPCR & G Protein
Molecular Formula
C16H18FNO2S
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
HY-101906-01DC260126
A19630-50DC260126 50mg
A19630-10DC260126 10mg
A19630-5DC260126 5mg
A19630-100DC260126 100mg
A19630-25DC260126 25mg
TBI1531-25MGDC260126, GPR40 antagonist
A19630-10mM-DDC260126 10mM * 1mL in DMSO

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