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T6167923

CAT: 0957-E8318-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E8318-01Size:5 mg
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Description
T6167923 is a selective MyD88-dependent signaling pathway inhibitor that directly interacts with the Toll/IL-1 receptor (TIR) domain of MyD88, preventing its homodimerization. This compound demonstrates inhibitory effects on NF-κB-mediated Staphylococcus enterotoxin AP (SEAP) activity and exhibits anti-inflammatory properties, with IC50 values of 2.7 μM (IFN-γ), 2.9 μM (IL-1β), 2.66 μM (IL-6), and 2.66 μM (TNF-α) .
CAS Number
2437475-16-4
Target
MyD88
Activity
Immunology & Inflammation
Molecular Formula
C17H20BrN3O3S2

Alternative Products

CatalogName
MBS5753995T6167923
M33136-01T6167923 B

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