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HGC652

CAT: 0957-E6651-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E6651-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HGC652 functions as a molecular glue by targeting E3 ubiquitin ligase TRIM21. It facilitates the formation of a TRIM21-NUP98 ternary complex, leading to degradation of NUP155 and nuclear pore complex proteins, ultimately resulting in cell death. The compound shows inhibitory effects on the proliferation of various cancer cell lines, with activity dependent on TRIM21 expression levels.
CAS Number
3055558-98-7
Target
Molecular Glues
Activity
Others
Molecular Formula
C23H28FNO3S2

Alternative Products

CatalogName
C18348-01HGC652

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