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3CAI

CAT: 0957-S6982-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-S6982-02Size:25 mg
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Description
3CAI is a specific and potent AKT1 and AKT2 inhibitor. 3CAI is a significantly more potent inhibitor of AKT1 than of PI3K. It markedly reduces AKT1 and AKT2 activity in a dose-dependent manner, leading to suppression of downstream AKT signaling and induction of apoptosis.
CAS Number
28755-03-5
Target
Akt
Activity
PI3K/Akt/mTOR

Chemical Information

3-Chloroacetylindole
CAS Number28755-03-5
PubChem CID152961
IUPAC Name2-chloro-1-(1H-indol-3-yl)ethanone
Molecular FormulaC10H8ClNO
Molecular Weight193.63
XLogP2.7
Topological Polar Surface Area32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Heavy Atom Count13
Formal Charge0
Complexity207
SMILES
C1=CC=C2C(=C1)C(=CN2)C(=O)CCl
InChI
InChI=1S/C10H8ClNO/c11-5-10(13)8-6-12-9-4-2-1-3-7(8)9/h1-4,6,12H,5H2
InChIKey
LLZQFAXTCYDVTR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-Chloroacetylindole
CAS: 28755-03-5
CID: 152961
Formula: C10H8ClNO
MW: 193.63
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight193.63
XLogP32.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass193.0294416
Monoisotopic Mass193.0294416
Topological Polar Surface Area32.9 Ų
Heavy Atom Count13
Formal Charge0
Complexity207
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
C17877-5mg3CAI
A20924-253CAI 25mg
A20924-503CAI 50mg
A20924-5003CAI 500mg
A20924-103CAI 10mg
A20924-2003CAI 200mg
A20924-1003CAI 100mg
A20924-53CAI 5mg
A20924-10mM-D3CAI 10mM * 1mL in DMSO
217170Akt Inhibitor XIX, 3CAI (2-Chloro-1- (1H-indol-3-yl) -ethanone, 3-Chloroacetyl-indole)

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