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BBO-8520

CAT: 0957-E1968-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-E1968-01Size:1 mg
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Description
BBO-8520 is a covalent small molecule inhibitor that selectively targets KRAS G12C with high oral bioavailability. It functions as both a KRAS G12C (OFF) inhibitor and a blocker of KRAS G12C (ON) signaling. The compound inhibits cellular proliferation by binding to GTP-bound KRAS G12C (ON), thereby preventing RAS-RAF1 interaction and promoting the transition to the inactive (OFF) state .
CAS Number
2893809-51-1
Target
Ras
Activity
Apoptosis
Molecular Formula
C35H33F6N7O2S

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