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Alofanib (RPT835)

CAT: 0957-S8754-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8754-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alofanib (RPT835) is a novel selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells. It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.
CAS Number
1612888-66-0
Target
FGFR
Activity
Protein Tyrosine Kinase
Molecular Formula
C19H15N3O6S
Storage Conditions
3 years -20°C powder

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