Products for Research Use Only

RAF709

CAT: 0957-S8690-01Size: 5 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0957-S8690-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
RAF709 is a potent inhibitor of B/C RAF kinase with almost equivalent IC50 values of 0.4 nM for B-RAF and C-RAF, showing a high level of selectivity, demonstrating greater than 99% on-target binding to BRAF, BRAFV600E, and CRAF at 1 μM and very few off-targets with DDR1 (>99%), DDR2 (86%), FRK (92%), and PDGFRb (96%), the only kinases with binding >80% at 1 μM.
CAS Number
1628838-42-5
Target
Raf
Activity
MAPK
Molecular Formula
C28H29F3N4O4
Storage Conditions
2 years -80 in solvent