RAF709 (Standard)

CAT: 0804-HY-100510RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-100510RSize:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
RAF709 (Standard) is the analytical standard of RAF709 (HY-100510) . This product is intended for research and analytical applications. RAF709 is a potent, selective, and efficacious RAF inhibitor with IC50s of 0.4 nM and 0.5 nM for BRAF and CRAF, respectively[1]. Antitumor efficacy[1].
CAS Number
[1628838-42-5]
Target
Raf; Reference Standards
Related Pathways
MAPK/ERK Pathway; Others
Field of Research
Cancer
Smiles
O=C(NC1=CN=C(C)C(C2=CC(N3CCOCC3)=C(OC4CCOCC4)N=C2)=C1)C5=CC=CC(C(F)(F)F)=C5
Molecular Formula
C28H29F3N4O4
Molecular Weight
542.55
References & Citations
[1]Nishiguchi GA, et al. Design and Discovery of N- (2-Methyl-5'-morpholino-6'- ((tetrahydro-2H-pyran-4-yl) oxy) -[3,3'-bipyridin]-5-yl) -3- (trifluoromethyl) benzamide (RAF709) : A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers. J Med Chem. 2017 Jun 22;60 (12) :4869-4881.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-100510-01RAF709
HY-B1074R-01Ethamsylate (Standard)
HY-119335RCyphenothrin (Standard)
HY-N0181R-01Ergosterol (Standard)
HY-N0699RDaphnoretin (Standard)
HY-B2102R-01Oxyphenisatine (Standard)
HY-N0284R-01Esculetin (Standard)
HY-B0115R-01Pizotifen (Standard)
HY-W422402RForamsulfuron (Standard)
HY-118827R-01Vedaprofen (Standard)

Alternative Products

CatalogName
BUP07438-01RAF709
A16842-5RAF709 5mg
A16842-25RAF709 25mg
A16842-50RAF709 50mg
A16842-100RAF709 100mg
A16842-500RAF709 500mg
A16842-1RAF709 1mg
A16842-2RAF709 2mg
A16842-10RAF709 10mg
A16842-10mM-DRAF709 10mM * 1mL in DMSO

Popular Products