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Selitrectinib (LOXO-195)

CAT: 0957-S8636-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8636-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selitrectinib (LOXO-195, BAY 2731954) is an orally available, highly potent, and selective TRK kinase inhibitor with low nanomolar inhibitory activity against TRKA G595R, TRKC G623R, and TRKA G667C, IC50s ranging from 2.0 to 9.8 nmol/L. It is more than 1,000-fold selective for 98% of non-TRK kinases tested.
CAS Number
2097002-61-2
Synonyms
BAY 2731954
Target
Trk receptor
Activity
Protein Tyrosine Kinase
Molecular Formula
C20H21FN6O
Storage Conditions
3 years -20°C powder

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